RAD9A

Across TCGA cell cohorts, RAD9A mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RAD9A-associated genes across cancer lineages are TBC1D21, OR6Q1, and CCDC105. Each is linked with RAD9A in more than 1 cancer types. Because this analysis shows association rather than direction, both RAD9A-to-partner and partner-to-RAD9A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TBC1D21 grouped by RAD9A-low versus RAD9A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD9A→partner) and Y-score (partner→RAD9A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TBC1D21 →	+0.010	+4.022	<.001	.006	3	1
LARGE_INTESTINE	OR6Q1 →	+0.015	+4.022	<.001	.006	3	1
BREAST	CCDC105 →	+0.006	+5.169	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

TBC1D21 by RAD9A expression — LARGE_INTESTINE

Explore this box plot interactively →