RAD54L2

Across TCGA cell cohorts, RAD54L2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,368 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RAD54L2-associated GO terms across cancer lineages are Heterochromatin formation, Negative regulation of gene expression, epigenetic, and Heterochromatin organization. Each is linked with RAD54L2 in more than 19 cancer types. Because this analysis shows association rather than direction, both RAD54L2-to-partner and partner-to-RAD54L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heterochromatin formation grouped by RAD54L2-low versus RAD54L2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD54L2→partner) and Y-score (partner→RAD54L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Heterochromatin formation →	+0.075	+0.710	.001	.002	3	20
LUNG_SCLC	Negative regulation of gene expression, epigenetic →	+0.069	+0.699	<.001	<.001	3	20
LUNG_NSCLC_LUSC	Heterochromatin organization →	+0.069	+0.709	<.001	.002	3	20
LUNG_SCLC	P-body assembly →	+0.115	+0.614	.001	.008	3	19
BONE	Epigenetic regulation of gene expression →	+0.067	+0.644	.003	.005	2	20
OESOPHAGUS	Nucleic acid transport →	+0.113	+0.644	<.001	.004	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,368 associations by consensus.

Heterochromatin formation by RAD54L2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →