RAD54L2

Across TCGA cell cohorts, RAD54L2 mutation is significantly associated with the RNA expression of many other genes, with 649 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RAD54L2-associated genes across cancer lineages are GSG1L2, OLIG3, and XKR4. Each is linked with RAD54L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAD54L2-to-partner and partner-to-RAD54L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSG1L2 grouped by RAD54L2-low versus RAD54L2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD54L2→partner) and Y-score (partner→RAD54L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GSG1L2 →	+0.043	+4.969	<.001	.003	3	2
PANCREAS	OLIG3 →	+0.006	+5.000	<.001	.006	3	1
PANCREAS	XKR4 →	+0.059	+5.000	<.001	.006	3	1
BLOOD_Myeloma	IYD →	+0.073	+3.716	.001	.005	3	1
BLOOD_Leukemia	C5orf67 →	+0.128	+4.409	<.001	.005	3	1
SKIN	TRIM72 →	+0.069	+2.378	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 649 associations by consensus.

GSG1L2 by RAD54L2 expression — BLOOD_Leukemia

Explore this box plot interactively →