RAD54B

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RAD54B mutation is significantly associated with the total protein of many other genes, with 47 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAD54B-associated genes across cancer lineages are MEK1, 14-3-3_beta, and eEF2. Each is linked with RAD54B in more than 2 cancer types. Because this analysis shows association rather than direction, both RAD54B-to-partner and partner-to-RAD54B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD54B→partner) and Y-score (partner→RAD54B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMEK1 →+0.256+1.415.034.04333
UCEC14-3-3_beta →-0.090-1.673.006.04032
UCECeEF2 →+0.254+1.392.031.01932
UCECeIF4E →+0.142+2.013.040.01632
UCECFoxM1 →+0.197+1.652.021.00632
UCECGAPDH →+0.483+2.906.006.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

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