Across TCGA patient cohorts, RAD51D mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAD51D-associated genes across cancer lineages are S6_pS240_S244, ASNS, and 14-3-3_beta. Each is linked with RAD51D in more than 1 cancer types. Because this analysis shows association rather than direction, both RAD51D-to-partner and partner-to-RAD51D results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD51D→partner) and Y-score (partner→RAD51D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	S6_pS240_S244 →	+0.429	+1.807	.005	.025	3	2
UCEC	ASNS →	+0.391	+2.000	.004	.029	3	2
UCEC	14-3-3_beta →	-0.126	-3.558	.001	.002	3	1
UCEC	ACC_pS79 →	+0.285	+2.459	.032	.018	3	1
UCEC	ACC1 →	+0.342	+1.678	.014	.023	3	1
UCEC	Ku80 →	+0.292	+2.100	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration

RAD51D survival (RNA) · tumor vs normal (RNA) · all RAD51D data types