RAD51B

Across TCGA cell cohorts, RAD51B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,510 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RAD51B-associated GO terms across cancer lineages are Microtubule nucleation, Homologous recombination, and Microtubule polymerization. Each is linked with RAD51B in more than 10 cancer types. Because this analysis shows association rather than direction, both RAD51B-to-partner and partner-to-RAD51B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule nucleation grouped by RAD51B-low versus RAD51B-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD51B→partner) and Y-score (partner→RAD51B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Microtubule nucleation →	+0.075	+0.938	.001	<.001	3	11
URINARY_TRACT	Homologous recombination →	+0.076	+0.904	.003	<.001	3	11
BLOOD_Leukemia	Microtubule polymerization →	+0.117	+0.893	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair →	+0.073	+0.967	<.001	.001	3	10
BREAST	Reciprocal meiotic recombination →	+0.070	+0.780	<.001	<.001	3	9
BLOOD_Leukemia	Microtubule polymerization or depolymerization →	+0.112	+0.955	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,510 associations by consensus.

Microtubule nucleation by RAD51B expression — SOFT_TISSUE

Explore this box plot interactively →