RAD51B

Across TCGA cell cohorts, RAD51B mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible RAD51B-associated genes across cancer lineages are LALBA, WFDC13, and MT1HL1. Each is linked with RAD51B in more than 1 cancer types. Because this analysis shows association rather than direction, both RAD51B-to-partner and partner-to-RAD51B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LALBA grouped by RAD51B-low versus RAD51B-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD51B→partner) and Y-score (partner→RAD51B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	LALBA →	+0.035	+4.922	<.001	.009	3	1
BLOOD_Leukemia	WFDC13 →	+0.021	+4.922	.002	.009	3	1
BLOOD_Leukemia	MT1HL1 →	+0.261	+4.922	.002	.009	3	1
SKIN	OR56A1 →	+0.019	+4.977	<.001	.007	3	1
SKIN	GALP →	+0.022	+5.415	<.001	.004	3	1
SKIN	MDFIC2 →	+0.155	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

LALBA by RAD51B expression — BLOOD_Leukemia

Explore this box plot interactively →