RAD51AP1

Across TCGA patient cohorts, RAD51AP1 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAD51AP1-associated genes across cancer lineages are 14-3-3_beta, EGFR_pY1068, and eIF4E. Each is linked with RAD51AP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAD51AP1-to-partner and partner-to-RAD51AP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 14-3-3_beta grouped by RAD51AP1-low versus RAD51AP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD51AP1→partner) and Y-score (partner→RAD51AP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.089	-2.973	.032	.035	3	1
UCEC	EGFR_pY1068 →	-0.253	-1.807	.014	.027	3	1
UCEC	eIF4E →	+0.196	+3.183	.024	.009	3	1
UCEC	ERK2 →	+0.169	+2.999	.033	.035	3	1
UCEC	INPP4B →	-0.289	-2.584	.030	.010	3	1
UCEC	JNK2 →	+0.232	+1.807	.004	.027	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

14-3-3_beta by RAD51AP1 expression — UCEC

Explore this box plot interactively →