RAD51

Across TCGA patient cohorts, RAD51 protein abundance is significantly associated with the RNA expression of many other genes, with 6,716 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RAD51-associated genes across cancer lineages are CSE1L, BUB1, and AURKA. Each is linked with RAD51 in more than 3 cancer types. Because this analysis shows association rather than direction, both RAD51-to-partner and partner-to-RAD51 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RAD51 versus CSE1L in GBM, with a Pearson correlation of 0.92.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD51→partner) and Y-score (partner→RAD51) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CSE1L →	+0.925	+0.359	.001	.001	3	4
UCEC	BUB1 →	+1.712	+1.034	<.001	<.001	3	4
UCEC	AURKA →	+1.160	+0.773	<.001	<.001	3	4
UCEC	KIF20A →	+1.753	+0.938	.001	.003	3	3
UCEC	CDC20 →	+1.626	+0.666	<.001	.004	3	3
UCEC	AUNIP →	+1.086	+1.030	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,716 associations by consensus.

RAD51 vs CSE1L — GBM

Explore this scatter interactively →