RAD51

Across TCGA cell cohorts, RAD51 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,358 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RAD51-associated GO terms across cancer lineages are Cellular response to cisplatin, Nuclear DNA replication, and Cell cycle DNA replication. Each is linked with RAD51 in more than 19 cancer types. Because this analysis shows association rather than direction, both RAD51-to-partner and partner-to-RAD51 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to cisplatin grouped by RAD51-low versus RAD51-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD51→partner) and Y-score (partner→RAD51) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Cellular response to cisplatin →	+0.265	+1.323	<.001	<.001	3	20
BONE	Nuclear DNA replication →	+0.200	+1.094	.002	.004	3	20
BONE	Cell cycle DNA replication →	+0.165	+0.976	.001	.003	3	20
LUNG_NSCLC_LUSC	Spindle elongation →	+0.311	+1.251	<.001	<.001	3	20
LUNG_NSCLC_LUAD	Kinetochore assembly →	+0.140	+0.868	<.001	<.001	3	20
LUNG_NSCLC_LUSC	DNA replication initiation →	+0.187	+1.247	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,358 associations by consensus.

Cellular response to cisplatin by RAD51 expression — SOFT_TISSUE

Explore this box plot interactively →