RAD51-AS1

Across TCGA pan-cancer cohorts, RAD51-AS1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated RAD51-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher RAD51-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated RAD51-AS1 expression acts as an unfavorable survival marker, although some lineages such as MESO and HNSC show a favorable association.

MESO, HNSC, and BLCA are the cancer types where RAD51-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	II,III,IV	0.499	0.286	.001	78	view →
HNSC	OS	Quartile	All	0.796	0.658	.003	67	view →
BLCA	OS	Tertile	All	0.808	0.640	<.001	57	view →
SKCM	OS	Quartile	All	0.381	0.223	<.001	46	view →
LIHC	DFS	Median	All	0.471	0.629	.001	39	view →
READ	OS	Median	III,IV	0.863	0.606	.002	39	view →
KIRC	DFS	Quartile	II,III,IV	0.350	0.621	.003	38	view →
ACC	DFS	Quartile	All	0.415	0.823	.001	32	view →
UCS	DFS	Median	IV	0.952	0.367	.001	24	view →
STAD	DFS	Quartile	IV	0.120	0.638	.011	17	view →
KICH	DFS	Quartile	II,III,IV	0.625	1.000	.012	13	view →
LGG	DFS	Median	All	0.797	0.862	.009	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

RAD51-AS1–MESO (OS)

Open the MESO breakdown →