RAD21

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RAD21 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,759 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RAD21-associated GO terms across cancer lineages are Protein localization to chromosome, centromeric region, Sister chromatid cohesion, and Positive regulation of mitotic cell cycle phase transition. Each is linked with RAD21 in more than 18 cancer types. Because this analysis shows association rather than direction, both RAD21-to-partner and partner-to-RAD21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to chromosome, centromeric region grouped by RAD21-low versus RAD21-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD21→partner) and Y-score (partner→RAD21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OESOPHAGUSProtein localization to chromosome, centromeric region →+0.176+1.157<.001<.001319
SOFT_TISSUESister chromatid cohesion →+0.117+0.793<.001<.001319
OESOPHAGUSPositive regulation of mitotic cell cycle phase transition →+0.122+1.027<.001<.001318
OESOPHAGUSProtein localization to kinetochore →+0.206+1.140<.001<.001318
UPPER_AERODIGESTIVE_TRACTMitotic sister chromatid cohesion →+0.139+1.108<.001<.001318
OESOPHAGUSPositive regulation of cell cycle process →+0.121+0.983<.001.001318
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,759 associations by consensus.

Protein localization to chromosome, centromeric region by RAD21 expression — OESOPHAGUS

Box plot of Protein localization to chromosome, centromeric region in RAD21-low vs RAD21-high samples in OESOPHAGUS.

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Exploration