RAD18

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RAD18 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RAD18-associated genes across cancer lineages are C14orf177. Each is linked with RAD18 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAD18-to-partner and partner-to-RAD18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C14orf177 grouped by RAD18-low versus RAD18-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD18→partner) and Y-score (partner→RAD18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaC14orf177 →+0.076+4.922<.001.00931
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

C14orf177 by RAD18 expression — BLOOD_Leukemia

Box plot of C14orf177 in RAD18-low vs RAD18-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration