RAD17

Across TCGA cell cohorts, RAD17 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RAD17-associated genes across cancer lineages are MRGPRE, KRTAP1-1, and TRPC5. Each is linked with RAD17 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAD17-to-partner and partner-to-RAD17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MRGPRE grouped by RAD17-low versus RAD17-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD17→partner) and Y-score (partner→RAD17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	MRGPRE →	+0.022	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	KRTAP1-1 →	+0.082	+5.209	<.001	.005	3	1
LARGE_INTESTINE	TRPC5 →	+0.015	+3.453	<.001	.009	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

MRGPRE by RAD17 expression — BLOOD_Lymphoma

Explore this box plot interactively →