RAD1

Across TCGA patient cohorts, RAD1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,110 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RAD1-associated genes across cancer lineages are NUP155, KNL1, and MMS22L. Each is linked with RAD1 in more than 4 cancer types. Because this analysis shows association rather than direction, both RAD1-to-partner and partner-to-RAD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RAD1 versus NUP155 in HNSC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD1→partner) and Y-score (partner→RAD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NUP155 →	+1.312	+0.433	<.001	<.001	3	5
LSCC	KNL1 →	+0.878	+0.278	<.001	<.001	3	5
LSCC	MMS22L →	+0.679	+0.249	<.001	<.001	3	5
BRCA	CDCA5 →	+0.915	+0.237	.001	<.001	3	5
LUAD	CIP2A →	+0.866	+0.294	<.001	<.001	3	5
LSCC	TYMS →	+0.927	+0.196	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,110 associations by consensus.

RAD1 vs NUP155 — HNSC

Explore this scatter interactively →