RAD1

Across TCGA cell cohorts, RAD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,949 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RAD1-associated GO terms across cancer lineages are Meiotic recombination checkpoint signaling, Protein localization to nuclear inner membrane, and Negative regulation of nuclear division. Each is linked with RAD1 in more than 19 cancer types. Because this analysis shows association rather than direction, both RAD1-to-partner and partner-to-RAD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Meiotic recombination checkpoint signaling grouped by RAD1-low versus RAD1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD1→partner) and Y-score (partner→RAD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Meiotic recombination checkpoint signaling →	+0.329	+1.280	<.001	<.001	3	20
OESOPHAGUS	Protein localization to nuclear inner membrane →	+0.165	+0.951	<.001	<.001	3	19
KIDNEY	Negative regulation of nuclear division →	+0.148	+0.947	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Establishment of mitotic sister chromatid cohesion →	+0.103	+0.974	<.001	<.001	3	16
LIVER	Negative regulation of meiotic nuclear division →	+0.331	+1.161	.001	.001	3	16
KIDNEY	Negative regulation of mitotic nuclear division →	+0.147	+0.916	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,949 associations by consensus.

Meiotic recombination checkpoint signaling by RAD1 expression — LIVER

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