RACGAP1

Across TCGA patient cohorts, RACGAP1 mutation is significantly associated with the RNA expression of many other genes, with 2,639 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RACGAP1-associated genes across cancer lineages are MTND4LP22, RN7SL856P, and LINC01708. Each is linked with RACGAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RACGAP1-to-partner and partner-to-RACGAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND4LP22 grouped by RACGAP1-low versus RACGAP1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RACGAP1→partner) and Y-score (partner→RACGAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MTND4LP22 →	+0.102	+5.408	<.001	.002	3	2
BLCA	RN7SL856P →	+0.101	+3.369	.002	.006	3	2
COAD	LINC01708 →	+0.127	+5.003	<.001	.004	3	2
CESC	RNU6-1122P →	+0.290	+5.969	<.001	.002	3	2
UCEC	LINC02210-CRHR1 →	+0.054	+2.366	.002	<.001	3	2
UCEC	RN7SL237P →	+0.186	+1.570	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,639 associations by consensus.

MTND4LP22 by RACGAP1 expression — SKCM

Explore this box plot interactively →