RACGAP1

Across TCGA cell cohorts, RACGAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,171 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RACGAP1-associated GO terms across cancer lineages are Negative regulation of cell cycle process, Microtubule cytoskeleton organization involved in mitosis, and Positive regulation of chromosome condensation. Each is linked with RACGAP1 in more than 19 cancer types. Because this analysis shows association rather than direction, both RACGAP1-to-partner and partner-to-RACGAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cell cycle process grouped by RACGAP1-low versus RACGAP1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RACGAP1→partner) and Y-score (partner→RACGAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of cell cycle process →	+0.081	+0.891	<.001	.001	3	20
STOMACH	Microtubule cytoskeleton organization involved in mitosis →	+0.126	+1.126	<.001	<.001	3	20
STOMACH	Positive regulation of chromosome condensation →	+0.210	+1.089	<.001	<.001	3	20
LUNG_NSCLC_LUSC	Mitotic spindle elongation →	+0.300	+1.275	<.001	.002	3	20
BREAST	Chromosome condensation →	+0.196	+1.267	<.001	<.001	3	20
OESOPHAGUS	Regulation of mitotic sister chromatid segregation →	+0.206	+1.208	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,171 associations by consensus.

Negative regulation of cell cycle process by RACGAP1 expression — OESOPHAGUS

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