RACGAP1

Across TCGA cell cohorts, RACGAP1 mutation is significantly associated with the drug of many other genes, with 28 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RACGAP1-associated genes across cancer lineages are Mirin, AGI-6780, and 729189. Each is linked with RACGAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RACGAP1-to-partner and partner-to-RACGAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mirin grouped by RACGAP1-low versus RACGAP1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RACGAP1→partner) and Y-score (partner→RACGAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Mirin →	+0.367	+2.868	.041	.022	3	1
LARGE_INTESTINE	AGI-6780 →	+0.369	+2.868	.045	.022	3	1
LARGE_INTESTINE	729189 →	+0.271	+2.871	.025	.021	2	2
LARGE_INTESTINE	Venetoclax →	+0.377	+2.777	.019	.038	3	1
LARGE_INTESTINE	Quizartinib →	+0.364	+2.874	.016	.021	3	1
LARGE_INTESTINE	IWP-2 →	+0.321	+3.115	.010	.015	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

Mirin by RACGAP1 expression — LARGE_INTESTINE

Explore this box plot interactively →