RAC2

Across TCGA patient cohorts, RAC2 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,577 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RAC2-associated proteins across cancer lineages are SPN, CCDC88B_S597, and CYBA. Each is linked with RAC2 in more than 9 cancer types. Because this analysis shows association rather than direction, both RAC2-to-partner and partner-to-RAC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RAC2 versus SPN in OV, with a Pearson correlation of 0.68.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RAC2→partner) and Y-score (partner→RAC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SPN →	+1.002	+1.335	<.001	<.001	3	10
CCRCC	CCDC88B_S597 →	+0.764	+1.168	<.001	<.001	3	10
GBM	CYBA →	+0.630	+0.864	<.001	<.001	3	10
GBM	CYBB →	+0.783	+0.887	<.001	<.001	3	10
GBM	DEF6 →	+0.734	+1.096	<.001	<.001	3	10
UCEC	DOCK10 →	+0.506	+1.011	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,577 associations by consensus.

RAC2 vs SPN — OV

Explore this scatter interactively →