RAC2

Across TCGA cell cohorts, RAC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,947 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible RAC2-associated GO terms across cancer lineages are Lymphocyte aggregation, Urokinase plasminogen activator signaling pathway, and Regulation of tolerance induction dependent upon immune response. Each is linked with RAC2 in more than 13 cancer types. Because this analysis shows association rather than direction, both RAC2-to-partner and partner-to-RAC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lymphocyte aggregation grouped by RAC2-low versus RAC2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAC2→partner) and Y-score (partner→RAC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Lymphocyte aggregation →	+1.225	+3.921	<.001	<.001	3	14
BREAST	Urokinase plasminogen activator signaling pathway →	+1.110	+2.824	<.001	<.001	2	14
LUNG_NSCLC_LUSC	Regulation of tolerance induction dependent upon immune response →	+1.523	+3.937	.001	<.001	3	12
LIVER	Positive regulation of leukocyte migration →	+0.129	+4.483	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Positive regulation of canonical NF-kappaB signal transduction →	+0.078	+3.734	<.001	<.001	3	12
OESOPHAGUS	Positive regulation of chemotaxis →	+0.147	+3.052	.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,947 associations by consensus.

Lymphocyte aggregation by RAC2 expression — BREAST

Explore this box plot interactively →