RAC1P8

Across TCGA patient cohorts, RAC1P8 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,346 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RAC1P8-associated GO terms across cancer lineages are Regulation of lipid localization, Cerebral cortex development, and Positive regulation of DNA repair. Each is linked with RAC1P8 in more than 5 cancer types. Because this analysis shows association rather than direction, both RAC1P8-to-partner and partner-to-RAC1P8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of lipid localization grouped by RAC1P8-low versus RAC1P8-high in UCEC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAC1P8→partner) and Y-score (partner→RAC1P8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Regulation of lipid localization →	+0.081	+0.057	<.001	<.001	3	5
UCEC	Cerebral cortex development →	+0.189	+0.039	<.001	.006	2	6
UCEC	Positive regulation of DNA repair →	+0.147	+0.040	<.001	.006	2	6
ESCA	Negative regulation of telomere maintenance via telomere lengthening →	+0.162	+0.054	<.001	.002	3	5
UCEC	Activation of GTPase activity →	+0.100	+0.045	<.001	.004	3	4
STAD	Regulation of plasma lipoprotein particle levels →	+0.060	+0.037	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,346 associations by consensus.

Regulation of lipid localization by RAC1P8 expression — UCEC

Explore this box plot interactively →