Across TCGA pan-cancer cohorts, RAC1P7 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RAC1P7’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where RAC1P7 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RAC1P7 is over-expressed in tumor.
KIRP and KIRC are the cancer types where RAC1P7 tumor–normal differential expression is most reproducible.