RAC1P4

Across TCGA pan-cancer cohorts, RAC1P4 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RAC1P4’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RAC1P4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RAC1P4 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

HNSC, LUAD, and BLCA are the cancer types where RAC1P4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RAC1P4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	All	+0.155	.002	6	view →
LUAD	All	All	+0.149	.007	4	view →
BLCA	Male	All	+0.150	.023	2	view →
KIRC	All	IV	−0.069	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RAC1P4–HNSC

Open the HNSC breakdown →