RABL6

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RABL6 mutation is significantly associated with the RNA expression of many other genes, with 309 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RABL6-associated genes across cancer lineages are HSCB, TRIM37, and PPIL4. Each is linked with RABL6 in more than 1 cancer types. Because this analysis shows association rather than direction, both RABL6-to-partner and partner-to-RABL6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RABL6→partner) and Y-score (partner→RABL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEHSCB →+0.562+3.169.003.00932
LARGE_INTESTINETRIM37 →+0.638+3.502.002.00132
LARGE_INTESTINEPPIL4 →+0.507+3.502.005.00132
LARGE_INTESTINESASS6 →+0.551+3.169.001.00932
LARGE_INTESTINELZIC →+0.629+3.502<.001.00132
LARGE_INTESTINEGLMN →+0.553+3.502.004.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 309 associations by consensus.

Exploration