Across TCGA cell cohorts, RABL6 mutation is significantly associated with the mutation status of many other genes, with 7,041 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RABL6-associated genes across cancer lineages are LETM1, PTPRC, and CELSR3. Each is linked with RABL6 in more than 3 cancer types. Because this analysis shows association rather than direction, both RABL6-to-partner and partner-to-RABL6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RABL6→partner) and Y-score (partner→RABL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	LETM1 →	+5.303	+4.339	<.001	<.001	1	4
LUNG_NSCLC_LUAD	PTPRC →	+2.981	+3.266	.009	.009	1	4
STOMACH	CELSR3 →	+2.440	+3.129	.003	.003	1	4
OVARY	MAP3K5 →	+4.977	+4.415	.007	.007	1	4
OVARY	ATAD3A →	+4.562	+5.217	<.001	<.001	1	4
BLOOD_Leukemia	LHX1 →	+5.247	+3.894	.001	.001	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,041 associations by consensus.

Exploration

RABL6 survival (RNA) · tumor vs normal (RNA) · all RABL6 data types