RABL2B

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RABL2B mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated RABL2B data layer compared with 21 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher RABL2B mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated RABL2B expression acts as an unfavorable survival marker.

PDAC, HNSC, and LUAD are the cancer types where RABL2B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
PDACOSMedianAll0.2750.438.0186view →
HNSCDFSMedianII,III,IV0.5370.797.0244view →
LUADDFSMedianII,III,IV0.7411.000.0381view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

RABL2B–PDAC (OS)

Kaplan–Meier survival curve for RABL2B mass-spec protein-high vs -low samples in PDAC.

Open the PDAC breakdown →

Exploration