RABIF

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RABIF mutation is significantly associated with the RNA expression of many other genes, with 96 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RABIF-associated genes across cancer lineages are OR6C76, RNU6-1336P, and PGAM1P1. Each is linked with RABIF in more than 1 cancer types. Because this analysis shows association rather than direction, both RABIF-to-partner and partner-to-RABIF results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RABIF→partner) and Y-score (partner→RABIF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADOR6C76 →+0.066+5.798<.001.00332
LUADRNU6-1336P →+0.524+5.481<.001.00532
LUADPGAM1P1 →+0.089+5.410<.001.00532
UCECSPAG11A →+0.458+2.644<.001.00531
UCECMETTL22 →+0.435+3.210.001.00931
COADKRTAP19-5 →+0.166+6.547.004.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 96 associations by consensus.

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