RABGEF1

Across TCGA patient cohorts, RABGEF1 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,829 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RABGEF1-associated proteins across cancer lineages are VKORC1L1, SBDS, and FBXL18. Each is linked with RABGEF1 in more than 3 cancer types. Because this analysis shows association rather than direction, both RABGEF1-to-partner and partner-to-RABGEF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RABGEF1 versus VKORC1L1 in UCEC, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RABGEF1→partner) and Y-score (partner→RABGEF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	VKORC1L1 →	+0.630	+0.394	<.001	.004	3	4
HNSC	SBDS →	+0.349	+0.421	.001	.006	2	4
CCRCC	FBXL18 →	+0.181	+0.285	.002	.002	3	3
LSCC	PDAP1 →	+0.302	+0.275	<.001	.005	3	3
GBM	WIPI2 →	+0.176	+0.284	.001	.001	3	3
LSCC	RSBN1L →	+0.285	+0.244	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,829 associations by consensus.

RABGEF1 vs VKORC1L1 — UCEC

Explore this scatter interactively →