RABGEF1

Across TCGA patient cohorts, RABGEF1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,672 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RABGEF1-associated genes across cancer lineages are FAM83D, HJURP, and CCNB2. Each is linked with RABGEF1 in more than 5 cancer types. Because this analysis shows association rather than direction, both RABGEF1-to-partner and partner-to-RABGEF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RABGEF1 versus FAM83D in LSCC, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RABGEF1→partner) and Y-score (partner→RABGEF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FAM83D →	-1.045	-0.131	<.001	.002	3	6
LUAD	HJURP →	-1.071	-0.167	<.001	<.001	3	6
BRCA	CCNB2 →	-0.939	-0.271	<.001	<.001	3	6
OV	ZCCHC24 →	+1.372	+0.228	<.001	<.001	3	6
LUAD	EXO1 →	-0.854	-0.135	<.001	<.001	3	6
BRCA	CDCA2 →	-1.054	-0.245	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,672 associations by consensus.

RABGEF1 vs FAM83D — LSCC

Explore this scatter interactively →