RABGEF1

Across TCGA cell cohorts, RABGEF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,708 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RABGEF1-associated GO terms across cancer lineages are Endocytic recycling, Cytosolic ribosome assembly, and Negative regulation of protein-containing complex disassembly. Each is linked with RABGEF1 in more than 14 cancer types. Because this analysis shows association rather than direction, both RABGEF1-to-partner and partner-to-RABGEF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endocytic recycling grouped by RABGEF1-low versus RABGEF1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RABGEF1→partner) and Y-score (partner→RABGEF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Endocytic recycling →	+0.065	+0.534	<.001	.001	3	15
PANCREAS	Cytosolic ribosome assembly →	+0.100	+0.619	.001	.003	3	14
SOFT_TISSUE	Negative regulation of protein-containing complex disassembly →	+0.108	+0.944	<.001	<.001	3	14
PANCREAS	Phosphatidylinositol biosynthetic process →	+0.064	+0.793	<.001	<.001	3	14
CNS	Endosomal transport →	+0.056	+0.724	<.001	<.001	3	14
PANCREAS	Phosphatidylinositol metabolic process →	+0.060	+0.732	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,708 associations by consensus.

Endocytic recycling by RABGEF1 expression — BONE

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