RABGAP1L

Across TCGA patient cohorts, RABGAP1L mutation is significantly associated with the total protein of many other genes, with 51 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RABGAP1L-associated genes across cancer lineages are INPP4B, p21, and PKC-delta_pS664. Each is linked with RABGAP1L in more than 1 cancer types. Because this analysis shows association rather than direction, both RABGAP1L-to-partner and partner-to-RABGAP1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INPP4B grouped by RABGAP1L-low versus RABGAP1L-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RABGAP1L→partner) and Y-score (partner→RABGAP1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	INPP4B →	-0.396	-3.161	.031	.019	3	2
UCEC	p21 →	+0.106	+1.106	.049	.020	3	2
UCEC	PKC-delta_pS664 →	-0.068	-0.947	.045	.047	3	2
UCEC	Rad50 →	-0.146	-1.489	.031	.025	3	2
UCEC	Annexin-1 →	+0.565	+2.736	<.001	<.001	3	2
UCEC	Shc_pY317 →	-0.154	-1.632	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

INPP4B by RABGAP1L expression — COAD

Explore this box plot interactively →