RABEP2

Across TCGA patient cohorts, RABEP2 mutation is significantly associated with the RNA expression of many other genes, with 2,898 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RABEP2-associated genes across cancer lineages are TOMM40, EMC8, and PRPF4. Each is linked with RABEP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both RABEP2-to-partner and partner-to-RABEP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TOMM40 grouped by RABEP2-low versus RABEP2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RABEP2→partner) and Y-score (partner→RABEP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TOMM40 →	+0.803	+3.494	<.001	.002	3	3
LUAD	EMC8 →	+0.520	+3.471	<.001	.002	3	3
UCEC	PRPF4 →	+0.563	+2.960	<.001	<.001	3	3
UCEC	ESCO2 →	+0.790	+3.818	<.001	<.001	3	3
LUAD	GSTA6P →	+0.227	+2.886	<.001	<.001	3	3
SKCM	ERI1 →	+0.714	+3.198	.002	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,898 associations by consensus.

TOMM40 by RABEP2 expression — LUAD

Explore this box plot interactively →