RABEP2

Across TCGA patient cohorts, RABEP2 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RABEP2-associated genes across cancer lineages are 4E-BP1, PCNA, and PDCD4. Each is linked with RABEP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both RABEP2-to-partner and partner-to-RABEP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 4E-BP1 grouped by RABEP2-low versus RABEP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RABEP2→partner) and Y-score (partner→RABEP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	4E-BP1 →	+0.329	+2.351	<.001	.003	3	3
LUAD	PCNA →	+0.251	+3.012	.004	.018	3	2
UCEC	PDCD4 →	-0.422	-1.847	.014	.008	3	2
UCEC	Rictor_pT1135 →	-0.079	-1.502	.036	.030	3	2
UCEC	ASNS →	+0.553	+2.321	<.001	.005	3	2
UCEC	C-Raf →	+0.176	+2.502	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

4E-BP1 by RABEP2 expression — UCEC

Explore this box plot interactively →