RABEP2

Across TCGA cell cohorts, RABEP2 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RABEP2-associated genes across cancer lineages are DMRTB1, OR1L3, and OR13C8. Each is linked with RABEP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RABEP2-to-partner and partner-to-RABEP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DMRTB1 grouped by RABEP2-low versus RABEP2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RABEP2→partner) and Y-score (partner→RABEP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	DMRTB1 →	+0.006	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR1L3 →	+0.028	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR13C8 →	+0.036	+5.662	<.001	.002	3	1
BLOOD_Leukemia	DCLK3 →	+0.208	+3.769	<.001	.008	3	1
BLOOD_Leukemia	OR1L6 →	+0.015	+4.060	.009	.003	3	1
BLOOD_Leukemia	TAS1R2 →	+0.011	+3.855	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

DMRTB1 by RABEP2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →