RAB6D

Across TCGA pan-cancer cohorts, RAB6D RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated RAB6D data layer compared with 1 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher RAB6D RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RAB6D expression acts as an unfavorable survival marker, although some lineages such as KIRC and BRCA show a favorable association.

LUSC, KIRC, and UVM are the cancer types where RAB6D RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Median	III,IV	0.522	0.776	<.001	73	view →
KIRC	OS	Median	All	0.733	0.538	<.001	63	view →
UVM	DFS	Quartile	II,III,IV	0.300	0.619	.002	44	view →
BRCA	DFS	Quartile	III,IV	0.952	0.786	<.001	36	view →
CHOL	OS	Median	III,IV	0.286	1.000	.008	30	view →
DLBC	DFS	Quartile	II,III,IV	0.126	0.951	<.001	24	view →
COAD	OS	Quartile	All	0.910	0.719	.008	19	view →
SKCM	DFS	Quartile	IV	0.090	0.773	<.001	16	view →
UCEC	OS	Tertile	All	0.825	0.898	.010	16	view →
ESCA	OS	Median	All	0.449	1.000	.011	14	view →
PCPG	OS	Median	All	0.778	1.000	.020	10	view →
TGCT	DFS	Quartile	All	0.963	0.702	.003	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

RAB6D–LUSC (DFS)

Open the LUSC breakdown →