Across TCGA patient cohorts, RAB6C mutation is significantly associated with the total protein of many other genes, with 50 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB6C-associated genes across cancer lineages are eEF2, Caspase-7-cleavedD198, and EGFR. Each is linked with RAB6C in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB6C-to-partner and partner-to-RAB6C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB6C→partner) and Y-score (partner→RAB6C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.383	+2.321	.004	.033	3	2
UCEC	Caspase-7-cleavedD198 →	+0.787	+2.242	<.001	.005	3	2
UCEC	EGFR →	-0.137	-2.169	.022	.003	3	1
UCEC	eIF4E →	+0.235	+2.662	.002	<.001	3	1
UCEC	A-Raf_pS299 →	-0.143	-1.807	.001	.025	3	1
UCEC	FOXO3a_pS318_S321 →	-0.147	-2.896	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

Exploration

RAB6C survival (RNA) · tumor vs normal (RNA) · all RAB6C data types