RAB5IF

Across TCGA cell cohorts, RAB5IF RNA expression is significantly associated with the go_rna of many other GO terms, with 3,166 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RAB5IF-associated GO terms across cancer lineages are Regulation of smooth muscle cell differentiation, Protein localization to mitochondrion, and Cell redox homeostasis. Each is linked with RAB5IF in more than 9 cancer types. Because this analysis shows association rather than direction, both RAB5IF-to-partner and partner-to-RAB5IF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of smooth muscle cell differentiation grouped by RAB5IF-low versus RAB5IF-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB5IF→partner) and Y-score (partner→RAB5IF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Regulation of smooth muscle cell differentiation →	-0.054	-0.456	<.001	.001	3	9
SKIN	Protein localization to mitochondrion →	+0.050	+0.781	<.001	<.001	2	10
SOFT_TISSUE	Cell redox homeostasis →	+0.071	+0.751	<.001	.001	3	8
BLOOD_Myeloma	Pyrimidine nucleoside monophosphate metabolic process →	+0.072	+0.739	.001	<.001	3	8
BLOOD_Myeloma	Pyrimidine nucleoside monophosphate biosynthetic process →	+0.081	+0.838	<.001	<.001	3	8
CNS	Positive regulation of smooth muscle cell differentiation →	-0.099	-0.538	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,166 associations by consensus.

Regulation of smooth muscle cell differentiation by RAB5IF expression — CNS

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