RAB5B

Across TCGA patient cohorts, RAB5B mutation is significantly associated with the RNA expression of many other genes, with 1,713 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB5B-associated genes across cancer lineages are RNA5SP419, HMGN2P34, and RNA5SP413. Each is linked with RAB5B in more than 2 cancer types. Because this analysis shows association rather than direction, both RAB5B-to-partner and partner-to-RAB5B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP419 grouped by RAB5B-low versus RAB5B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB5B→partner) and Y-score (partner→RAB5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP419 →	+0.476	+2.077	.001	.003	3	3
SKCM	HMGN2P34 →	+0.106	+3.408	.004	.009	3	2
UCEC	RNA5SP413 →	+1.040	+1.862	<.001	.004	3	2
UCEC	RNA5SP417 →	+0.478	+2.936	<.001	<.001	3	2
UCEC	RNA5SP421 →	+0.457	+1.903	.008	.004	3	2
UCEC	RNA5SP420 →	+0.405	+1.967	.003	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,713 associations by consensus.

RNA5SP419 by RAB5B expression — UCEC

Explore this box plot interactively →