RAB4B-EGLN2

Across TCGA pan-cancer cohorts, RAB4B-EGLN2 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated RAB4B-EGLN2 data layer.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher RAB4B-EGLN2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RAB4B-EGLN2 expression acts as an unfavorable survival marker, although some lineages such as PAAD and LUAD show a favorable association.

OV, COAD, and HNSC are the cancer types where RAB4B-EGLN2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Tertile	II,III,IV	0.274	0.390	.010	62	view →
COAD	OS	Quartile	All	0.757	0.913	.003	51	view →
HNSC	OS	Median	III,IV	0.547	0.776	.002	42	view →
MESO	OS	Tertile	III,IV	0.460	0.663	.003	39	view →
KIRC	DFS	Quartile	All	0.515	0.717	.006	37	view →
LGG	OS	Tertile	All	0.383	0.597	<.001	33	view →
ACC	DFS	Tertile	All	0.328	0.682	.003	23	view →
THCA	DFS	Median	III,IV	0.735	0.925	.011	19	view →
KIRP	DFS	Quartile	III,IV	0.424	0.866	.001	18	view →
STAD	DFS	Median	IV	0.142	0.493	.016	12	view →
UVM	OS	Tertile	All	0.399	0.853	.010	12	view →
PAAD	OS	Quartile	All	0.537	0.288	.025	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

RAB4B-EGLN2–OV (OS)

Open the OV breakdown →