RAB43

Across TCGA patient cohorts, RAB43 mutation is significantly associated with the RNA expression of many other genes, with 237 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB43-associated genes across cancer lineages are KRTAP20-3, RBMY1F, and RNA5SP173. Each is linked with RAB43 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB43-to-partner and partner-to-RAB43 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP20-3 grouped by RAB43-low versus RAB43-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB43→partner) and Y-score (partner→RAB43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KRTAP20-3 →	+0.098	+4.890	<.001	.002	3	2
KIRC	RBMY1F →	+0.094	+8.025	<.001	.007	3	1
KIRC	RNA5SP173 →	+0.134	+8.025	<.001	.007	3	1
KIRC	RNU6-477P →	+0.164	+8.025	<.001	.007	3	1
KIRC	RNU6-614P →	+0.164	+8.025	<.001	.007	3	1
KIRC	RNU4-37P →	+0.204	+8.025	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 237 associations by consensus.

KRTAP20-3 by RAB43 expression — UCEC

Explore this box plot interactively →