Across TCGA pan-cancer cohorts, RAB42P1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RAB42P1’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RAB42P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RAB42P1 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.
KIRC and LUSC are the cancer types where RAB42P1 tumor–normal differential expression is most reproducible.