Across TCGA pan-cancer cohorts, RAB42 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated RAB42 data layer compared with 23 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher RAB42 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated RAB42 expression acts as an unfavorable survival marker.

BRCA, KIRP, and UCEC are the cancer types where RAB42 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.350	0.924	<.001	36	view →
KIRP	DFS	Median	All	0.277	0.867	.004	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: RAB42 tumor-vs-normal RNA expression · all RAB42 data types