RAB40AL

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RAB40AL mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RAB40AL-associated genes across cancer lineages are HTR2A, SULT1E1, and LCT. Each is linked with RAB40AL in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB40AL-to-partner and partner-to-RAB40AL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HTR2A grouped by RAB40AL-low versus RAB40AL-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB40AL→partner) and Y-score (partner→RAB40AL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYHTR2A →+0.034+4.029<.001.00931
LARGE_INTESTINESULT1E1 →+1.456+3.541<.001.00431
LARGE_INTESTINELCT →+0.300+3.464.002.00431
LARGE_INTESTINEC3orf20 →+0.073+3.464.006.00431
LARGE_INTESTINEPOM121L2 →+0.081+3.464.003.00431
LARGE_INTESTINEPROKR1 →+0.039+3.648.003.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

HTR2A by RAB40AL expression — OVARY

Box plot of HTR2A in RAB40AL-low vs RAB40AL-high samples in OVARY.

Explore this box plot interactively →

Exploration