RAB40AL

mutation — cross-omics
Cross-omicsMUTATION → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RAB40AL mutation is significantly associated with the mutation status of many other genes, with 1,540 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RAB40AL-associated genes across cancer lineages are CLRN2, TSC2, and PLA2G4C. Each is linked with RAB40AL in more than 2 cancer types. Because this analysis shows association rather than direction, both RAB40AL-to-partner and partner-to-RAB40AL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLRN2 grouped by RAB40AL-low versus RAB40AL-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB40AL→partner) and Y-score (partner→RAB40AL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYCLRN2 →+4.977+4.415.007.00713
OVARYTSC2 →+2.977+4.273.006.00612
OVARYPLA2G4C →+4.977+4.415.007.00712
OVARYALDH2 →+4.977+4.415.007.00712
OVARYRPAP2 →+5.562+5.562<.001<.00112
OVARYHERC3 →+4.977+4.415.007.00712
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,540 associations by consensus.

CLRN2 by RAB40AL expression — OVARY

Box plot of CLRN2 in RAB40AL-low vs RAB40AL-high samples in OVARY.

Explore this box plot interactively →

Exploration