RAB40A

Across TCGA pan-cancer cohorts, RAB40A Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated RAB40A data layer compared with 18 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher RAB40A Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated RAB40A expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

SKCM, COAD, and UCEC are the cancer types where RAB40A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	All	0.230	0.781	.004	24	view →
COAD	DFS	Median	II,III,IV	0.177	0.758	<.001	15	view →
UCEC	DFS	Median	III,IV	0.906	0.532	.038	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

RAB40A–SKCM (OS)

Open the SKCM breakdown →