RAB3IL1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RAB3IL1 mutation is significantly associated with the RNA expression of many other genes, with 1,655 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB3IL1-associated genes across cancer lineages are RNU1-17P, MIR760, and POM121C. Each is linked with RAB3IL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB3IL1-to-partner and partner-to-RAB3IL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-17P grouped by RAB3IL1-low versus RAB3IL1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB3IL1→partner) and Y-score (partner→RAB3IL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNU1-17P →+0.156+2.087.003.00932
UCECMIR760 →+0.315+1.834.001.00232
UCECPOM121C →+0.517+1.931<.001.00931
UCECDOC2B →-1.027-2.247<.001.00231
UCECDCP1A →+0.504+2.158.002.00931
UCECCWC25 →+0.409+2.922.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,655 associations by consensus.

RNU1-17P by RAB3IL1 expression — UCEC

Box plot of RNU1-17P in RAB3IL1-low vs RAB3IL1-high samples in UCEC.

Explore this box plot interactively →

Exploration