RAB3IL1

Across TCGA cell cohorts, RAB3IL1 mutation is significantly associated with the RNA expression of many other genes, with 47 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RAB3IL1-associated genes across cancer lineages are PRM3, RXFP3, and PABPC1L2B. Each is linked with RAB3IL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB3IL1-to-partner and partner-to-RAB3IL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRM3 grouped by RAB3IL1-low versus RAB3IL1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB3IL1→partner) and Y-score (partner→RAB3IL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	PRM3 →	+0.133	+4.754	<.001	.005	3	1
CNS	RXFP3 →	+0.063	+4.169	<.001	.008	3	1
UPPER_AERODIGESTIVE_TRACT	PABPC1L2B →	+0.099	+4.736	.009	.009	3	1
BLOOD_Leukemia	CCKAR →	+0.038	+4.409	<.001	.005	3	1
BLOOD_Leukemia	NPSR1 →	+0.023	+4.152	.001	.009	3	1
BLOOD_Leukemia	GUCA2A →	+0.039	+4.969	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

PRM3 by RAB3IL1 expression — CNS

Explore this box plot interactively →