RAB3GAP2

Across TCGA patient cohorts, RAB3GAP2 mutation is significantly associated with the RNA expression of many other genes, with 5,514 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB3GAP2-associated genes across cancer lineages are FOXD2-AS1, LIN7C, and CCSAP. Each is linked with RAB3GAP2 in more than 3 cancer types. Because this analysis shows association rather than direction, both RAB3GAP2-to-partner and partner-to-RAB3GAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FOXD2-AS1 grouped by RAB3GAP2-low versus RAB3GAP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB3GAP2→partner) and Y-score (partner→RAB3GAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FOXD2-AS1 →	+0.372	+1.662	.001	.003	3	4
UCEC	LIN7C →	+0.533	+1.243	<.001	<.001	3	3
UCEC	CCSAP →	+0.463	+1.606	<.001	<.001	3	3
UCEC	GBP5 →	+1.091	+2.010	<.001	<.001	3	3
UCEC	BUB3 →	+0.410	+2.174	<.001	<.001	3	3
UCEC	CHAF1B →	+0.691	+2.000	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,514 associations by consensus.

FOXD2-AS1 by RAB3GAP2 expression — UCEC

Explore this box plot interactively →