RAB3GAP2

Across TCGA cell cohorts, RAB3GAP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,454 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RAB3GAP2-associated GO terms across cancer lineages are Establishment of protein localization to endoplasmic reticulum membrane, Regulation of formation of translation preinitiation complex, and Negative regulation of formation of translation preinitiation complex. Each is linked with RAB3GAP2 in more than 19 cancer types. Because this analysis shows association rather than direction, both RAB3GAP2-to-partner and partner-to-RAB3GAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to endoplasmic reticulum membrane grouped by RAB3GAP2-low versus RAB3GAP2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB3GAP2→partner) and Y-score (partner→RAB3GAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Establishment of protein localization to endoplasmic reticulum membrane →	+0.175	+1.181	<.001	<.001	3	20
OVARY	Regulation of formation of translation preinitiation complex →	+0.087	+0.600	.001	.003	3	16
OVARY	Negative regulation of formation of translation preinitiation complex →	+0.087	+0.600	.001	.003	3	16
LUNG_SCLC	Positive regulation of protein lipidation →	+0.160	+0.777	<.001	<.001	3	16
LUNG_SCLC	Positive regulation of lipoprotein metabolic process →	+0.160	+0.777	<.001	<.001	3	16
LARGE_INTESTINE	mRNA export from nucleus →	+0.093	+0.640	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,454 associations by consensus.

Establishment of protein localization to endoplasmic reticulum membrane by RAB3GAP2 expression — LUNG_NSCLC_LUSC

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